2026-10-29T01:46:46Z https://lifeofresearch.com/oai2

oai:lifeofresearch.com:152 2026-10-28T21:44:56Z type:article openaire

The Role of Estrogen and Progesterone in Hormone Receptor-Positive Breast Cancer Safya Ahmed Abdullah Algazar Breast Cancer Estrogen Progesterone Hormone Receptors Hormone Receptor-Positive Breast Cancer Endocrine Therapy Hormonal Signaling Treatment Resistance Breast cancer is one of the most common cancers among women, and is defined as a disease in which abnormal and uncontrolled growth of breast cells occurs, and these cells may be transmitted to other parts of the body if the disease is not detected and treated in a timely manner. The study of biological factors associated with the growth of breast cancer is important, especially hormones such as oestrogen and progesterone, because of the growth and reproduction processes of breast cells that are regulated. Scientific studies have shown that some breast cells, including some cancer cells, are expressed by oestrogen and progesterone receptors. When these hormones are linked to their receptors, the growth and reproduction of some breast cancer cells may be stimulated. Therefore, the presence of hormone receptors was considered an important factor that is used in the classification of some types of breast cancer and determining their response to hormone therapy. Attention has been paid to the study of the relationship between hormones and breast cancer because of the role that estrogen and progesterone may play in regulating the growth of breast tissue. It was also explained that the relationship between hormones and the development of breast cancer is complex, and does not depend on the effect of only one hormone, but may be affected by the interaction between hormones and their receptors and various cellular and molecular factors. Life of Research 2026-10-28 info:eu-repo/semantics/article https://lifeofresearch.com/articles/152 eng https://lifeofresearch.com/articles/152/files/161/Research%201-2.pdf application/pdf https://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess